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Cysteine peptide

Published Time:2023-03-28Views:1917

CAT#:P013439

Name :Cysteine peptide

CAS#: 

Sequence: Ac-RFAACAA-OH (Ac-Arg-Phe-Ala-Ala-Cys-Ala-Ala-OH)

Molecular Formula: C32H50N10O9S

MW: 750.86

Appearance:white powder

Purity(HPLC):95%

Delivery:Fedex door to door service ,3-7 days

Free Sample: No

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100mg$150.00In Stock
1g$550.00In Stock
5g$2000.00In Stock
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Ac-RFAACAA-OH is a synthetic peptide that is commonly used in DPRA as a representative peptide for skin sensitization testing. The peptide contains cysteine residues, which are important for its reactivity with sensitizing chemicals.

 

DPRA using Ac-RFAACAA-OH involves exposing the peptide to the test chemical and measuring the extent of peptide reactivity. The reaction is typically monitored by measuring the consumption of the peptide and the formation of adducts between the peptide and the test chemical. If the peptide is consumed and adducts are formed, it indicates that the test chemical is potentially sensitizing.

 

DPRA using Ac-RFAACAA-OH has been found to be a reliable and accurate method for predicting skin sensitization potential of chemicals. The method has been validated and accepted by regulatory agencies, such as the European Chemicals Agency (ECHA), as an alternative to animal testing for skin sensitization.

 

Overall, Ac-RFAACAA-OH is an important tool for evaluating the safety of chemicals and reducing the need for animal testing. Its use in DPRA helps to identify potentially sensitizing chemicals and supports the development of safer products for human use.


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